Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Cell Division Cycle (CDC) » Anti -Structural Maintenance of Chromosomes 1, phosphorylated (Ser966) (SMC1, bK268H5, bK268H5.5, CDLS2, DKFZp686L19178, DXhXs423e, DXS423E, FLJ43748, KIAA0178, MGC138332, OTTHUMP00000061876, RP6-29D12.1, Sb1.8, SB1.8/DXS423E Protein, Segregation of Mitotic Chr

Anti -Structural Maintenance of Chromosomes 1, phosphorylated (Ser966) (SMC1, bK268H5,
bK268H5.5, CDLS2, DKFZp686L19178, DXhXs423e, DXS423E, FLJ43748, KIAA0178, MGC138332,
OTTHUMP00000061876, RP6-29D12.1, Sb1.8, SB1.8/DXS423E Protein, Segregation of Mitotic Chr

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP
Structural maintenance of chromosomes (SMC) proteins are part of the cohesin and condensin multisubunit complexes that play a critical role in chromosome organization, segregation, gene regulation, and DNA repair. The core cohesin complex includes a heterodimer of SMC1 and SMC3 that functions by forming a ring-like structure that holds sister chromatids together. Cohesin is important to sister chromatid separation and segregation during mitosis and meiosis and also plays a role in double-strand break repair by homologous recombination.
Catalog #S7980-01F1
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Cellular Localization Nuclear
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in TBS, pH 7.2, 0.1% BSA, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenRabbits were immunized with a phosphorylated synthetic peptide, which represented the portion of human Structural Maintenance of Chromosomes-1 (LocusLink ID 8243) around Serine 966, conjugated to KLH. After multiple immunizations in Freund's adjuvant, serum was collected. Antibodies that were not phospho-specific were removed by solid phase absorption. Antibodies specific for SMC1 pSer957 were affinity purified using the phosphopeptide immobilized on solid support.
SpecificityReacts with human SMC1 phosphoSerine 966. Other species have not been tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links