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You are here:Home » Antibodies » Antibodies-Cell Division Cycle (CDC) » Anti -Structural Maintenance of Chromosomes 1 Like 1, phosphorylated (Ser966) (SMC1, SMC1L1)

Anti -Structural Maintenance of Chromosomes 1 Like 1, phosphorylated (Ser966) (SMC1,


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP
SMC1 is a member of the evolutionary highly conserved SMC family of ATPases which play a vital role in the organization of chromosomes during mitosis. Eukaryotic SMC1 combines with SMC3, and with the two sister-chromatid cohesion proteins Scc1 and Scc3, to form the macromolecular cohesion complex, responsible for the linking of sister chromatids during metaphase. The SMC1-SMC3 heterodimer also combines with DNA polymerase E and ligase III to form the DNA recombination complex RC-1.
Catalog #S7980-01K
ApplicationsSuitable for use in Immunoprecipitation and Western Blot. Other applications not tested
Recommended DilutionImmunoprecipitation: 2-6ug/mg lysate
Western Blot: 1:500-1:5000detects a band of ~160kD in HeLa whole cell lysates.
Optimal dilution to be determined by researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
FormSupplied as a liquidi n TBS, 0.09% sodium azide and 0.1% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic phosphopeptide corresponding to an amino acid sequence within SMC1, which includes phosphorylated Ser966.
SpecificityRecognizes the human nuclear protein SMC1 (structural maintenance of chromosomes 1), when phosphorylated at Ser966.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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