Anti -Structural Maintenance of Chromosomes 3 (Structural Maintenance of Chromosome 3,
SMC3, SMC-3, BAM, Bamacan, Basement Membrane-associated Chondroitin Proteoglycan, BMH,
Chondroitin Sulfate Proteoglycan 6, CSPG6, Chromosome-associated Polypeptide, hCAP, SMC
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP IC |
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| Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis and in chromosome movement. | | | Catalog # | S7982-03 | | Applications | Suitable for use in Western Blot, Immunoprecipitation and Immunocytochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 1:1000-1:10,000 | | Immunoprecipitation: 2-6ul/mg | | Immunocytochemistry: 1:200-1:800 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in Tris-citrate/phosphate buffer, pH 7-8, 0.09% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Human Structural Maintenance of Chromosomes 3. | | Epitope | Maps to a region between residue 1175 and the C-terminus (residue 1217) of human Structural Maintenance of Chromosomes 3 | | Specificity | Recognizes human Structural Maintenance of Chromosomes 3. Species Crossreactivity: Xenopus | | Species Sequence Homology | Mouse, bovine | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Structural Maintenance of Chromosomes 3 (Structural Maintenance of Chromosome 3, SMC3, SMC-3, BAM, Bamacan, Basement Membrane-associated Chondroitin Proteoglycan, BMH, Chondroitin Sulfate Proteoglycan 6, CSPG6, Chromosome-associated Polypeptide, hCAP, SMC |
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