Anti -Structural Maintenance of Chromosomes 3 (SMC3, SMC-3, BAM, Bamacan, Basement
Membrane-associated Chondroitin Proteoglycan, BMH, Chondroitin Sulfate Proteoglycan 6,
CSPG6, Chromosome-associated Polypeptide, hCAP, SMC3L1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
IH |
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| This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. | | | Catalog # | S7982-03A | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (paraffin): 1:100-1:500. Antigen retrieval with citrate buffer will enhance staining. Lkely to work with frozen sections. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in TBS, pH 7.2, 0.1% BSA, 0.1% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | The epitope recognized maps to a region between residues 1175 and C-terminus (residue 1217) of human Structural Maintenance of Chromosome 3 using the numbering given in entry NP_005436.1 (GeneID 9126). | | Specificity | Species Crossreactivity: Human and mouse. Other species have not been tested. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Structural Maintenance of Chromosomes 3 (SMC3, SMC-3, BAM, Bamacan, Basement Membrane-associated Chondroitin Proteoglycan, BMH, Chondroitin Sulfate Proteoglycan 6, CSPG6, Chromosome-associated Polypeptide, hCAP, SMC3L1) |
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