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You are here:Home » Antibodies » Abs to Cell Division Cycle (CDC) » Anti -Structural Maintenance of Chromosomes 3 (SMC3, SMC-3, BAM, Bamacan, Basement Membrane-associated Chondroitin Proteoglycan, BMH, Chondroitin Sulfate Proteoglycan 6, CSPG6, Chromosome-associated Polypeptide, hCAP, SMC3L1) (Agarose)

Anti -Structural Maintenance of Chromosomes 3 (SMC3, SMC-3, BAM, Bamacan, Basement
Membrane-associated Chondroitin Proteoglycan, BMH, Chondroitin Sulfate Proteoglycan 6,
CSPG6, Chromosome-associated Polypeptide, hCAP, SMC3L1) (Agarose)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IP
Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis and in chromosome movement.
Catalog #S7982-03E
ApplicationsSuitable for use in Immunoprecipitation. Other applications not tested.
Recommended DilutionsImmunoprecipitation: 15-25ul gel/0.1-1mg protein lysate
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot Determined
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Conjugated to agarose.
PurityPurified by immunoaffinity chromatography.
ImmunogenHuman SMC3.
SpecificityRecognizes human SMC3. Species sequence homology: mouse and bovine
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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