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Specifications

Clone Host Grade Applications Monoclonal Mouse Affinity Purified E IH

The tachykinins belong to an evolutionary conserved family of peptide neurotransmitters that share the C-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an established role in neurotransmission. The mammalian tachykinins include substance P, neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.
Catalog #	S8000-01A
Applications	Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended Dilution	ELISA: 1:10,000
	Immunohistochemistry (human): 1:1000
	Immunohistochemistry (rat): 1:2000
	Optimal dilutions to be determined by the researcher.
Storage and Stability	Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	n/a
Clone Type	Monoclonal
Isotype	IgG1
Clone No	9L669
Host	Mouse
Source	Human
Concentration	~1mg/ml
Form	Supplied as a lyophilized powder from 0.1M glycine PBS, pH 7.4. No preservative added. Reconstitute in 100ul sterile ddH2O.
Purity	Purified by Protein A affinity chromatography.
Immunogen	Synthetic peptide corresponding to human Substance P (RPRPQQFFGLM).
Specificity	Recognizes human Substance P. No cross reactivity against Neurokinin A, Neurokinin B or Kassinin. Species Crossreactivity: rat
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.