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Anti -Substance P (NK, Neurokinin)
Anti -Substance P (NK, Neurokinin)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Guinea pig |
Serum |
IH IF |
|
| The tachykinins belong to an evolutionary conserved family of peptide neurotransmitters that share the C-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an established role in neurotransmission. The mammalian tachykinins include substance P, neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma. | | | Catalog # | S8000-02 | | Applications | Suitable for use in Immunofluorescence and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry: 1:250-1:1000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Guinea pig | | Source | Rat | | Concentration | Not determined | | Form | Supplied as a liquid in PBS, pH 7.2, 0.05% sodium azide. | | Purity | Serum | | Immunogen | Synthetic peptide corresponding to aa1-11, CRPKPQQFFGLM, of rat Substance P. | | Specificity | Recognizes rat Substance P. Species Crossreactivity: Human, mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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