You are here:Home
»
Antibodies
»
Abs to Substance P
»
Anti -Substance P, aa4-11 (NK, Neurokinin)
Anti -Substance P, aa4-11 (NK, Neurokinin)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
IH |
|
| Substance P occurs in nerve fibers of the central and peripheral nervous system and in endocrine cells of the gut. It stimulates smooth muscle contraction, gives rise to vasodilation and is involved in sensory functions. Substance P-containing tumors arising in the ileum are | | | often associated with the carcinoid syndrome, characterized by flushing of the skin, diarrhea, bronchoconstriction and sudden drops in blood pressure. Substance P is commonly found in the midgut carcinoids and some of the symptoms may be related to this peptide. | | | Catalog # | S8000-05D | | Applications | Suitable for use in Immunohistochemistry (frozen and paraffin-embedded tissue, no proteolytic treatment required). | | Recommended Dilution | Immunohistochemistry: 1:400-1:800 using PAP, with overnight incubation at 2-8°C. | | Positive Control | Frozen sections of rat colon. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20°C or colder. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Concentration | Not determined | | Form | Supplied as a liquid. | | Purity | Serum | | Immunogen | Synthetic Substance P 4-11, conjugated to thyroglobulin using CDI. | | Specificity | Recognizes Substance P. Absorption with 10-100ug SP 1-4 per ml diluted antiserum abolishes the staining. Species Crossreactivity: Human and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
