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You are here:Home » Antibodies » Antibodies-Substance P » Anti -Substance P (NK, Neurokinin)

Anti -Substance P (NK, Neurokinin)


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Clone Host Grade Applications
Monoclonal Rat Supernatant IH
The tachykinins belong to an evolutionary conserved family of peptide neurotransmitters that share the C-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an established role in neurotransmission. The mammalian tachykinins include substance P, neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.
Catalog #S8000-12
Application(s) 1:1001:200 by immunohistochemistry on human brain.
Clone TypeMonoclonal
Clone No2Q111
ConcentrationNot determined
FormSupplied as a liquid containing 0.01% thimerosal.
PurityTissue culture supernatant.
ImmunogenSubstance P conjugated to BSA
SpecificityReacts with COOH-terminal end of Substance P. No crossreactivity to Leu-or Metenkephalin, somatostatin or beta-endorphin. Eledoisin 5%
Species ReactivityAnimal and human.
Important NoteThis product is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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