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Specifications

Clone Host Grade Applications Monoclonal Rat Supernatant IH

The tachykinins belong to an evolutionary conserved family of peptide neurotransmitters that share the C-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an established role in neurotransmission. The mammalian tachykinins include substance P, neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.
Catalog #	S8000-12
Application(s)	1:100–1:200 by immunohistochemistry on human brain.
CAS Number	n/a
Clone Type	Monoclonal
Isotype	IgG2a
Clone No	2Q111
Host	Rat
Source	Human
Concentration	As reported
Form	Supplied as a liquid containing 0.01% thimerosal.
Purity	Tissue culture supernatant.
Immunogen	Substance P conjugated to BSA
Specificity	Reacts with COOH-terminal end of Substance P. No crossreactivity to Leu-or Metenkephalin, somatostatin or beta-endorphin. Eledoisin 5%
Species Reactivity	Animal and human.
Important Note	This product is intended for research use only, not for use in human, therapeutic or diagnostic applications.