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You are here:Home » Antibodies » Antibodies-Substance P » Anti -Substance P Receptor, aa385-407 (NK1 Receptor, Neurokinin Receptor)

Anti -Substance P Receptor, aa385-407 (NK1 Receptor, Neurokinin Receptor)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum B IH
The tachykinins belong to an evolutionary conserved family of peptide neurotransmitters that share the C-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an established role in neurotransmission. The mammalian tachykinins include substance P, neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.
Catalog #S8000-50
ApplicationsSuitable for use in Immunohistochemistry and Western Blot. Other applications not tested.
Recommended DilutionImmunohistochemistry (Paraformaldehyde-fixed cryostat or Vibratome sections): 1:100-1:1000
Western Blot: 1:500. Detects truncated form of Substance P Receptor on 10ug of mouse brain lysates.
Optimal dilutions to be determined by the researcher.
Positive Control Spinal Cord
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceRat
ConcentrationNot determined
FormSupplied as a liquid with no preservatives.
PuritySerum
ImmunogenSynthetic peptide corresponding to aa385-407 of rat Substance P Receptor (NM_003173).
SpecificityRecognizes rat Substance P Receptor expressing neurons in the central nervous system at 35kD. Species Crossreactivity: mouse, guinea pig.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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