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Anti -Substance P Receptor, aa385-407 (NK1 Receptor, Neurokinin Receptor)
Anti -Substance P Receptor, aa385-407 (NK1 Receptor, Neurokinin Receptor)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
IH |
|
| The tachykinins belong to an evolutionary conserved family of peptide neurotransmitters that share the C-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an established role in neurotransmission. The mammalian tachykinins include substance P, neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine, headache and allergy-induced asthma. | | | Catalog # | S8000-51 | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilutions | Immunohistochemistry: 1:100-1:1000 | | Optimal dilution to be determined by researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Mouse | | Concentration | Not determined | | Form | Liquid. No preservatives added. | | Purity | Serum | | Immunogen | Synthetic peptide that corresponds to a 23 amino acid sequence (385-407) of the COOH-terminus of the mouse/rat Substance P Receptor (NK-1R). | | Specificity | Recognizes mouse Substance P Receptor (NK-1R). Species Crosseactivity: Rat and guinea pig. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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