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You are here:Home » Antibodies » Abs to Substance P » Anti -Substance P Receptor, aa385-407 (NK1 Receptor, Neurokinin Receptor)

Anti -Substance P Receptor, aa385-407 (NK1 Receptor, Neurokinin Receptor)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum B IH
Substance P is a tachykinin family neuropeptide that functions as a neurotransmitter and neuromodulator. In the CNS, Substance P is involved in the regulation of mood, anxiety, sleep, saiety, reinforcement, respiratory rhythm and pain processing. In nociception, the neuropeptide is released at local spinal cord synapses. Recent research now shows substance P is potentially involved in endothelial cell differentiation as well as diverse roles in neuroinflammatory response. The endogenous receptor for Substance P is neurokinin 1 receptor (NK1 receptor), which belongs to the tachykinin receptor sub-family of GPCRs.
Catalog #S8000-51
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionsImmunohistochemistry: 1:100-1:1000
Western Blot: 1:500 detected the truncated form of Substance P Receptor on 10ug of mouse brain membrane lysates
Optimal dilution to be determined by researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceMouse
ConcentrationNot Determined
FormLiquid. No preservatives added.
PuritySerum
ImmunogenSynthetic peptide that corresponds to aa385-407 from the COOH-terminus of the mouse/rat Substance P Receptor (NK-1R).
SpecificityRecognizes mouse Substance P Receptor (NK-1R).
Species CrosseactivityRat and guinea pig.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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