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Abs to Superoxide Dismutase
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Anti -Superoxide Dismutase, Cu,Zn (SOD1)
Anti -Superoxide Dismutase, Cu,Zn (SOD1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E IH |
|
| Catalog # | S8060-14E | | Superoxide dismutases (SOD) are a class of enzymes that catalyze the dismutation of superoxide into oxygen and hydrogen peroxide. As such, they are an important antioxidant defense in nearly all cells exposed to oxygen. There are three major families of superoxide dismutase, depending on the metal cofactor | Cu-Zn (which binds both copper and zinc), Fe and Mn types (which bind either iron or manganese), and finally the Ni type, which binds nickel. | | Applications | Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. | | Recommended Dilutions | Immunohistochemistry (Paraffin): Does not require pre-treatment (trypsin or pronase) prior to staining or antigen retrieval using heat treatment methods prior to staining of paraffin sections. | | Immunohistochemistry: Frozen sections | | Optimal dilutions to be determined by the researcher. | | Positive Control | Human spleen and lymph node. | | Hybridoma | Sp-2/0-Ag14 myeloma cell line with spleen cells from immunized mice. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 10F478 | | Host | Mouse | | Source | Bovine | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, 0.1% BSA, 0.09% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Superoxide dismutase enzyme prepared from bovine erythrocytes. | | Specificity | Recognizes bovine Superoxide Dismutase, Cu, Zn. Does not cross react with immunoglobulins but does react weakly with Mn SOD. Species Crossreactivity: human and mouse | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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