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You are here:Home » Antibodies » Abs to Enzymes, Methyltransferase » Anti -SUV420H2, ID (Histone-lysine N-methyltransferase SUV420H2, Suppressor of Variegation 4-20 Homolog 2, Su(var)4-20 Homolog 2, Suv4-20h2, Lysine N-methyltransferase 5C, PP7130, KMT5C)

Anti -SUV420H2, ID (Histone-lysine N-methyltransferase SUV420H2, Suppressor of Variegation
4-20 Homolog 2, Su(var)4-20 Homolog 2, Suv4-20h2, Lysine N-methyltransferase 5C, PP7130,
KMT5C)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B
SUV420H2 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2).
Catalog #S8096-05
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by ammonium sulfate precipitation.
ImmunogenSynthetic peptide selected from the Center region of human SUV420H2 (KLH).
SpecificityRecognizes human SUV420H2. Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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