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Abs to Enzymes, Methyltransferase
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Anti -SUV420H2, ID (Histone-lysine N-methyltransferase SUV420H2, Suppressor of Variegation 4-20 Homolog 2, Su(var)4-20 Homolog 2, Suv4-20h2, Lysine N-methyltransferase 5C, PP7130, KMT5C)
Anti -SUV420H2, ID (Histone-lysine N-methyltransferase SUV420H2, Suppressor of Variegation 4-20 Homolog 2, Su(var)4-20 Homolog 2, Suv4-20h2, Lysine N-methyltransferase 5C, PP7130, KMT5C)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Purified |
E B |
|
| SUV420H2 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2). | | | Catalog # | S8096-05 | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 1:1,000 | | Western Blot: 1:50-1:100 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.25mg/ml | | Form | Supplied as a liquid in PBS, 0.09% sodium azide. | | Purity | Purified by ammonium sulfate precipitation. | | Immunogen | Synthetic peptide selected from the Center region of human SUV420H2 (KLH). | | Specificity | Recognizes human SUV420H2. Species Crossreactivity: mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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