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You are here:Home » Antibodies » Abs to RNA Processing » Anti -Survival of Motor Neuron 1, Telomeric (Survival of Motor Neuron 1 (Telomeric), SMNT, Survival of Motor Neuron 1, Survival Motor Neuron 1 Protein, SMN1, BCD541, Component of Gems 1, Gemin 1, Gemin-1, SMA, SMA@, SMA1, SMA2, SMA3, SMA4, SMNC, Survival Motor

Anti -Survival of Motor Neuron 1, Telomeric (Survival of Motor Neuron 1 (Telomeric), SMNT,
Survival of Motor Neuron 1, Survival Motor Neuron 1 Protein, SMN1, BCD541, Component of
Gems 1, Gemin 1, Gemin-1, SMA, SMA@, SMA1, SMA2, SMA3, SMA4, SMNC, Survival Motor

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified B IP IC
Survival of Motor Neuron 1 (SMN, Germin 1) is the central component of a large oligomeric complex (SMN complex), including Gemins 2-7, that is necessary and sufficient for the in vivo assembly of Sm proteins onto the small nuclear (sn)RNAs that mediate pre-mRNA splicing. The SMN complex is found in the cytoplasm and nucleus. Within the nucleus, this protein localizes to subnuclear bodies called gems which are found near coiled bodies containing high concentrations of small ribonucleoproteins (snRNPs). Spinal muscular atrophy, a motor neuron disorder, results from reduced levels or a mutation in the Gemin 1 protein.
Catalog #S8495-03
ApplicationsSuitable for use in Western Blot, Immunoprecipitation and Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1-2ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlA431 whole cell lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No9E762
HostMouse
SourceHuman
Concentration~2mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
PurityPurified
ImmunogenRecombinant corresponding to human Survival of Motor Neuron 1, Telomeric. Cellular Localization: Cytoplasmic, nuclear
SpecificityRecognizes human Survival of Motor Neuron 1, Telomeric at ~35kD. Species Crossreactivity: Mouse, Xenopus laevis
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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