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You are here:Home » Antibodies » Abs to Apoptosis » Anti -Survivin (Apoptosis Inhibitor 4, Apoptosis Inhibitor-4, API4, Apoptosis Inhibitor Survivin, Baculoviral IAP Repeat-containing 5, BIRC5, BIRC-5, EPR1, EPR-1, IAP4, SVV, TIAP)

Anti -Survivin (Apoptosis Inhibitor 4, Apoptosis Inhibitor-4, API4, Apoptosis Inhibitor
Survivin, Baculoviral IAP Repeat-containing 5, BIRC5, BIRC-5, EPR1, EPR-1, IAP4, SVV,
TIAP)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IH IF
Survivin, a new inhibitor of apoptosis (IAP) protein, is expressed in the G2/M phase of the cell cycle in a cycle-regulated manner. At the beginning of mitosis, survivin associates with microtubules of the mitotic spindle in a specific and saturable reaction that is regulated by microtubule dynamics. Disruption of survivin-microtubule interactions results in loss of survivin.
Catalog #S8500-01N
ApplicationsSuitable for use in Immunofluorescence and Immunohistochemistry. Not suitable for use in Western Blot. Other applications not tested.
Recommended DilutionImmunofluorescence: 1:200 for 2 hours on human prostate cells
Immunohistochemistry (FFPE): 2-4ug/ml for 30 minutes at RT. Requires boiling tissue in 10mM citrate buffer for 10-20 minutes followed by cooling at RT for 10-20 minutes.
Optimal dilutions to be determined by the researcher.
Positive ControlHeLa cells
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No9E764
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.09% sodium azide, 0.2% BSA.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant full length human Survivin. Epitope: aa 1- 99.
Cellular LocalizationCytoplasmic
SpecificityRecognizes human Survivin. Species Crossreactivity: rat
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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