You are here:Home
»
Antibodies
»
Abs to Tyrosine Kinases
»
Anti -SYK, phosphorylated (Tyr525/526) (Tyrosine-protein Kinase SYK, Spleen Tyrosine Kinase)
Anti -SYK, phosphorylated (Tyr525/526) (Tyrosine-protein Kinase SYK, Spleen Tyrosine
Kinase)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B IH |
|
| Syk is a positive effector of BCR-stimulated responses. This protein couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-342 and Tyr-346. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion. | | | Catalog # | S9100-01U | | Applications | Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | ELISA: 1:1,000 | | Western Blot: 1:100-1:500 | | Immunohistochemistry: 1:50-1:100 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.25mg/ml | | Form | Supplied as a liquid in PBS, 0.09% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr525/526 of human Syk (KLH). | | Specificity | Recognizes human Syk when phosphorylated at Tyr525 and 526.. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
