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You are here:Home » Antibodies » Abs to Synaptophysin » Anti -Synaptophysin (SYP, SYPH, SypI, Major Synaptic Vesicle Protein P38, Syn p38) (FITC)

Anti -Synaptophysin (SYP, SYPH, SypI, Major Synaptic Vesicle Protein P38, Syn p38) (FITC)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IH IF
Synaptophysin labels normal neuroendocrine cells of human adrenal medulla, carotid body, skin, pituitary gland, thyroid, lung, pancreas, gastrointestinal mucosa, Paneth’s cells in the gastrointestinal tract and of gastric parietal cells. Neurons in the brain, spinal cord, and retina are also labeled. Anti-synaptophysin reacts with neuroendocrine neoplasms of neural as well as epithelial types e.g. neuroblastomas, ganglioneuroblastomas. ganglioneuromas, pheo-chromocytomas, chromaffin, and non-chromaffin paragangliomas. Of the epithelial types include pituitary adenomas, islet cell neoplasms, medullathyroid carcinomas, parathyroid adenomas, carcinoids of the bronchopulmonary and gastro-intestinal tracts and neuroendocrine carcinomas of the skin. In combination with anti-chromogranin A and anti-NSE, anti-synaptophysin is very useful in the identification of normal neuroendocrine cells and neuroendocrine neoplasms.
Catalog #S9108-09E
ApplicationsSuitable for use in Immunofluorescence microscopy and Immunohistochemistry. Other applications not tested.
Recommended DilutionsImmunofluorescence microscopy: 1:10 with PBS, pH 7.4; Incubation Time: 1 hour at RT.
Immunohistochemistry: Frozen tissue and cytological material. No protease treatment required.
Optimal dilutions to be determined by the researcher.
Reactivities on Cultured Cell LinesRat PC-12 cell line.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. FITC conjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG1
Clone No5F304
HostMouse
SourceBovine
ConcentrationNot Determined
FormSupplied as a liquid. Labeled with fluorescein isothiocyanate (FITC).
PurityPurified by Protein A affinity chromatography.
ImmunogenSynaptophysin from presynaptic vesicles, prepared from bovine brain.
SpecificityRecognizes bovine Synaptophysin. An excellent marker for several neuroendocrine, neuronal and adrenal tumors. Neuronal and adrenal tumors such as pheochromocytomas, paragangliomas, neuroblastomas, ganglioneuroblastomas. Neuroendocrine tumors of epithelial origin
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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