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You are here:Home » Antibodies » Antibodies-Synaptophysin » Anti -Synaptophysin

Anti -Synaptophysin


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Clone Host Grade Applications
Monoclonal Mouse Ascites B IH IF
Synaptophysin labels normal neuroendocrine cells of human adrenal medulla, carotid body, skin, pituitary gland, thyroid, lung, pancreas, gastrointestinal mucosa, Paneth’s cells in the gastrointestinal tract and of gastric parietal cells. Neurons in the brain, spinal cord, and retina are also labelled. Anti-synaptophysin reacts with neuroendocrine neoplasms of neural as well as epithelial types e.g. neuroblastomas, ganglioneuroblastomas. ganglioneuromas, pheo-chromocytomas, chromaffin, and non-chromaffin paragangliomas. Of the epithelial types include pituitary adenomas, islet cell neoplasms, medullathyroid carcinomas, parathyroid adenomas, carcinoids of the bronchopulmonary and gastro-intestinal tracts and neuroendocrine carcinomas of the skin. In combination with anti-chromogranin A and anti-NSE, anti-synaptophysin is very useful in the identification of normal neuroendocrine cells and neuroendocrine neoplasms.
Catalog #S9108-11
ApplicationsSuitable for use in Immunohistochemistry, Immunoflourescence and Western Blot. Other applications not tested.
Recommended DilutionImmunohistochemistry/Immunoflourescence (Frozen, paraffin): 1:100-1:200 using indirect immunoperoxidase on formalin-fixed, paraffin embedded rat cerebellum.
Western Blot: 1:500 detected Synatophysin on 10ug of mouse brain lysates.
Optimal dilution determined by the researcher.
ControlBrain Tissue
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
Clone No2Q105
ConcentrationNot Determined
FormSupplied as a liquid, 0.1% sodium azide.
ImmunogenRat retina synaptophysin (Accession# NM_003179.2)
SpecificityRecognizes rat Synaptophysin at ~40kD. Localizes the 38kD band of rat synaptophysin by immunoblotting. Stains synaptophysin in neurons, neuromuscular junctions, paraganglia cells, pancreatic islet cells, anterior lymphomas and adrenal cells. Detects synaptophysin in many types of benign and malignant neural and epithelial neuroendocrine neoplasmas. Species crossreactivity: human, guinea pig, porcine, mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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