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You are here:Home » Antibodies » Abs to Synaptophysin » Anti -Synaptophysin

Anti -Synaptophysin

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites E B IH
Synaptophysin labels normal neuroendocrine cells of human adrenal medulla, carotid body, skin, pituitary gland, thyroid, lung, pancreas, gastrointestinal mucosa, Paneth’s cells in the gastrointestinal tract and of gastric parietal cells. Neurons in the brain, spinal cord, and retina are also labeled. Anti-synaptophysin reacts with neuroendocrine neoplasms of neural as well as epithelial types e.g. neuroblastomas, ganglioneuroblastomas. ganglioneuromas, pheo-chromocytomas, chromaffin, and non-chromaffin paragangliomas. Of the epithelial types include pituitary adenomas, islet cell neoplasms, medullathyroid carcinomas, parathyroid adenomas, carcinoids of the bronchopulmonary and gastro-intestinal tracts and neuroendocrine carcinomas of the skin. In combination with anti-chromogranin A and anti-NSE, anti-synaptophysin is very useful in the identification of normal neuroendocrine cells and neuroendocrine neoplasms.
Catalog #S9108-13
ApplicationsSuitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications have not been tested.
Recommended Dilutions
Immunohistochemistry: 1:5000 on formalin-fixed human brain (hippocampus) using the Immunoperoxidase technique. Also stains paraffin embedded human tissue at 1:200 using the ABC technique.
Western Blot: 1:2500-1:10,000
ELISA: 1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgM
Clone No2Q107
HostMouse
SourceHuman
ConcentrationNot Determined
FormSupplied as a liquid.
PurityAscites
ImmunogenCrude human synaptic immunoprecipitate
SpecificityRecognizes human Synaptophysin. Reacts with synaptophysin expressed in CHO cells. Species Crossreactivity: porcine, hamster, feline and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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