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You are here:Home » Antibodies » Antibodies-Syntaxin, Synaptotagmin, Synaptophysin » Anti -Synaptotagmin, phosphorylated (Ser309) (SYT, DKFZp781D2042, P65, SVP65, Synaptotagmin I, SYT1, SYT-1, SytI, SYT2, SYT3)

Anti -Synaptotagmin, phosphorylated (Ser309) (SYT, DKFZp781D2042, P65, SVP65,
Synaptotagmin I, SYT1, SYT-1, SytI, SYT2, SYT3)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Synaptotagmin is widely regarded as the primary calcium sensor for synaptic vesicle exocytosis (Fernandez-Chacon et al., 2001; Wang et al., 2003). Moreover recent studies indicate that the protein also plays a key role in endocytosis (Poskanzer et al., 2003). Synaptotagmin can be phosphorylated by multiple protein kinases and this may play a key role in modulation of synaptotagmin ability to influence both the exocytotic and endocytotic components of synaptic transmission (Hilfiker et al., 1999; Lee et al., 2004).
Catalog #S9108-99B1
ApplicationsSuitable for use in Dot Blot and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
ConcentrationNot determined
Form10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg per ml BSA and 50% glycerol
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic phosphopeptide corresponding to amino acids residues surrounding the phospho Ser309 of synaptotagmin. The sequence of the immunogen is identical in synaptotagmin I, II and III in human, mouse and rat.
SpecificitySpecific for the ~60 - 62k Synaptotagmin protein phosphorylated at Ser309 in Western Blots of rat brain lysates. Species Crossreactivity: This antibody recognizes the rat form of the protein.
Other species have not been tested. Human, mouse, and rat have 100% amino acid sequence identity with the antigen used to raise the antibody.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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