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You are here:Home » Antibodies » Abs to Syntaxin, Synaptotagmin, Synaptophysin » Anti -Synaptotagmin I/II (Synaptotagmin-1, SytI, p65, SYT1, SVP65, SYT, Synaptotagmin-2, SytII, SYT2)

Anti -Synaptotagmin I/II (Synaptotagmin-1, SytI, p65, SYT1, SVP65, SYT, Synaptotagmin-2,
SytII, SYT2)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
The synaptotagmin family has been implicated in calcium-dependent neurotransmitter release, although Synaptotagmin I (Syt I) is the only isoform that controls synaptic vesicle fusion. Synaptotagmins have calcium-dependent membranetrafficking functions on both sides of the synapse. Synaptotagmins also play key roles in synaptic vesicle endocytosis. Synaptotagmin’s ability to influence both the exocytotic and endocytotic components of synaptic transmission may be modulated by its phosphorylation.
Catalog #S9109-24A
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot:1:500-1:1,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic non-phosphopeptide corresponding to human Synaptotagmin I/II around the phosphorylation site of threonine 202/199 (R-K-TP-L-N).
SpecificityRecognizes human Synaptotagmin I/II. Species Cross-Reactivity: mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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