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You are here:Home » Antibodies » Abs to Syntaxin, Synaptotagmin, Synaptophysin » Anti -Syntaxin 2 (Epimorphin)

Anti -Syntaxin 2 (Epimorphin)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP IH
Syntaxin 2, also known as epimorphin, is a 35kD type II integral membrane that belongs to the t-SNARE family, a group of proteins involved in protein transport (2). Syntaxin 2 was first identified as a factor that promotes branching morphogenesis in mammary epithelial cells (3). Studies using pancreatic exocrine acinar cells, in which the exocytic pathways are well defined, show primary localization of syntaxin 2 to the apical plasma membrane (4). Homologs of syntaxin 2 have been identified in various eukaryotes ranging from yeast to human (5, 6). Neuronal syntaxin is a component of a 20S complex implicated in vesicle docking and fusion, which involves its interaction with syntaxin through a ATP-dependent reaction modulated by synaptotagmin, SNAP-25, alpha-SNAP, and NSF (7).
Applications:
Suitable for use in Western Blot, Immunohistochemistry and Immunoprecipitation. Other applications not tested.
Catalog #S9205-06
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Positive ControlsJurkat Cell Lysate
HeLa Cell Lysate
Rat Brain Tissue Extract
Mouse Brain Tissue Extract
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceRat
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the sequence near the N-terminus of rat Syntaxin 2.
SpecificityRecognizes rat Syntaxin 2 at ~35kD. Species Crossreactivity: human, mouse, bovine, canine, chicken, Drosophila, hamster, monkey, porcine, rabbit, sheep and Xenopus.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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