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You are here:Home » Antibodies » Abs to Syntaxin, Synaptotagmin, Synaptophysin » Anti -STXBP1 (Syntaxin-binding Protein 1, MUNC18-1, N-Sec1, Protein Unc-18 Homolog 1, Unc18-1, Protein Unc-18 Homolog A, Unc-18A, p67, UNC18A)

Anti -STXBP1 (Syntaxin-binding Protein 1, MUNC18-1, N-Sec1, Protein Unc-18 Homolog 1,
Unc18-1, Protein Unc-18 Homolog A, Unc-18A, p67, UNC18A)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
Catalog #S9205-80A
May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 11 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:16,000
Western Blot: 0.1-0.3ug/ml, observed in human and mouse brain lysates on ~75kD bands
Immunohistochemistry (Paraffin): 5-10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-SRVSFEDQAPTME, from STXBP1, at C-terminal (NP_003156.1).
SpecificityRecognizes STXBP1. Species Crossreactivity: Human and mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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