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You are here:Home » Antibodies » Abs to Synuclein » Anti -Synuclein, alpha (Alpha-synuclein, SNCA, MGC110988, Non-A beta Component of AD Amyloid, Non-A4 Component of Amyloid Precursor, NACP, PARK1, PARK4, PD1)

Anti -Synuclein, alpha (Alpha-synuclein, SNCA, MGC110988, Non-A beta Component of AD
Amyloid, Non-A4 Component of Amyloid Precursor, NACP, PARK1, PARK4, PD1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Alpha-synuclein is a presynaptic neuronal protein that is thought to be involved in the formation of SNARE complexes. Most significantly, aggregated alpha-synuclein is one of the major components found in the Lewy bodies that occur in Parkinsonís disease (PD) and other neurodegenerative disorders. Mutation of the alpha-synuclein gene is associated with familial forms of PD. Recent evidence suggests that phosphorylation of alpha-synuclein at ser129 plays a role in the formation of inclusions in PD.
Catalog #S9500-03U
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:1000
Optimal dilutions to be determined by the researcher.
Positive ControlK562 cells
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic non-phosphopeptide corresponding to human a-Synuclein around the phosphorylation site of tyrosine 125 (E-A-YP-E-M ).
SpecificityRecognizes human a-Synuclein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesSynuclein, alpha (Non A4 Component of Amyloid Precursor)


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