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Specifications

Clone Host Grade Applications Polyclonal Goat Serum E IH

Catalog #	S9500-12
Recommended Secondary Reagents	Donkey anti-SheepGoat IgG: HRP
Recommended Positive Control Tissue	Brain, Spinal Cord.
Applications	Immunohistochemistry: Paraffin. 1:300
	ELISA: 1:1000 vs immunizing peptide
	Optimal working dilutions to be determined by researcher.
Immunohistochemistry	This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.
CAS Number	n/a
Clone Type	Polyclonal
Isotype	IgG
Host	Goat
Source	Human
Concentration	Not determined
Form	Serum. Supplied as a liquid with 0.1% sodium azide.
Purity	Serum.
Immunogen	Synthetic peptide corresponding to amino acids 116-131 of the C-terminus of a synuclein.
Specificity	Recognizes human alpha-synuclein. The alpha-synuclein gene, located on chromosome 4, has been linked to early onset autosomal dominant Parkinson's disease. The protein is abundant in the nervous system and is known to be the precursor of the non-beta amyloid component protein (NACP) of Alzheimer's disease. Alpha-synuclein has also been found to be associated with other neurodegenerative diseases such as multiple system atrophy and dementia with Lewy's bodies.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.