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You are here:Home » Antibodies » Abs to Synuclein » Anti -Synuclein, alpha (Alpha-synuclein, Non-A beta Component of AD Amyloid, Non-A4 Component of Amyloid Precursor, NACP, SNCA, NACP, PARK1)

Anti -Synuclein, alpha (Alpha-synuclein, Non-A beta Component of AD Amyloid, Non-A4
Component of Amyloid Precursor, NACP, SNCA, NACP, PARK1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified Gel
alpha-Synuclein is a 19kD protein composed of 140aa and a member of the synuclein family. Synucleins have been specifically implicated in three diseases: Alzheimer's (AD), Parkinson's (PD) and breast cancer. In AD, a peptide derived from alpha- synuclein forms an intrinsic component of plaque amyloid. In PD, an alpha-synuclein allele is genetically linked to several independent familial cases, and the protein appears to accumulate in Lewy bodies. In breast cancer, increased expression of gamma-synuclein correlates with disease progression.
Catalog #S9500-21T
ApplicationsSuitable for use in Dot Blot. Other applications not tested.
Recommended DilutionDot Blot: 1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.05 % sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide (GAG-S-IAA) corresponding to human alpha-Synuclein, surrounding serine 87.
SpecificityRecognizes human alpha Synuclein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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