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Anti -Synuclein, alpha, Phosphorylated (Ser87) (Alpha-synuclein, Non-A beta Component of AD Amyloid, Non-A4 Component of Amyloid Precursor, NACP, SNCA, NACP, PARK1)
Anti -Synuclein, alpha, Phosphorylated (Ser87) (Alpha-synuclein, Non-A beta Component of
AD Amyloid, Non-A4 Component of Amyloid Precursor, NACP, SNCA, NACP, PARK1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
Gel |
|
| alpha-Synuclein is a 19kD protein composed of 140aa and a member of the synuclein family. Synucleins have been specifically implicated in three diseases: Alzheimer's (AD), Parkinson's (PD) and breast cancer. In AD, a peptide derived from alpha- synuclein forms an intrinsic component of plaque amyloid. In PD, an alpha-synuclein allele is genetically linked to several independent familial cases, and the protein appears to accumulate in Lewy bodies. In breast cancer, increased expression of gamma-synuclein correlates with disease progression. | | | Catalog # | S9500-21U | | Applications | Suitable for use in Dot Blot. Other applications not tested. | | Recommended Dilution | Dot Blot: 1ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.05 % sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic phosphopeptide (GAG-pS-IAA) corresponding to human alpha-Synuclein, at the phosphorylated serine 87. | | Specificity | Recognizes human alpha Synuclein when Phosphorylated at Ser87.. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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