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You are here:Home » Antibodies » Abs to Synuclein » Anti -Synuclein, gamma (BCSG1)

Anti -Synuclein, gamma (BCSG1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Description: Synucleins are small, soluble proteins expressed primarily in neural tissue and in certain tumors. The family includes three known proteins: a-synuclein, B-synuclein, and Y-synuclein. All synucleins have in common a highly conserved a-helical lipid-binding motif with similarity to the class-A2 lipid-binding domains of the exchangeable apolipoproteins. Although they are homologous, each synuclein is encoded by a different gene on chromosomes 4q21.3-q22. Y-Synuclein (also called BCSG-1) is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer.
Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.
Catalog #S9502-17
Recommended DilutionWestern Blot: 1:500-1:2000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
FormSupplied as a liquid in PBS, pH 7.4, 0.02% thimerosal
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant human Y-Synuclein (E. coli)
SpecificityRecognizes human Y-synuclein and does not cross-react with a- and B-synuclein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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