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You are here:Home » Antibodies » Abs to Synuclein » Anti -Synuclein, pan

Anti -Synuclein, pan

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum B IH
Catalog #S9505
Synucleins are small, soluble proteins expressed primarily in neural tissue and in certain tumors. The family includes three known proteins alpha-synuclein, beta-synuclein, and gamma-synuclein. The alpha- and beta-synuclein proteins are found primarily in brain tissue, where they are seen mainly in presynaptic terminals. The gamma-synuclein protein is found primarily in the peripheral nervous system and retina, but its expression in breast tumors is a marker for tumor progression.
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:1000
Immunohistochemistry: 1:1000 on frozen and paraffin embedded tissue.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a lyophilized powder. Contains no preservative. Reconstitute with 50ul of sterile ddH2O.
PuritySerum
ImmunogenSynthetic peptide corresponding to aa11-26 of human alpha, beta, and gamma (82%)-synuclein protein. The peptide was chosen so that the antibody would recognize all three forms of synuclein
SpecificityRecognizes human Synuclein, pan. Staining pattern overlaps alpha, beta and gamma-synuclein maps. Species crossreactivity: rat
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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