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You are here:Home » Antibodies » Antibodies-Signal Transduction » Anti -Talin (TLN, Talin 1, Talin-1, TLN1, ILWEQ, KIAA1027)

Anti -Talin (TLN, Talin 1, Talin-1, TLN1, ILWEQ, KIAA1027)


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Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IP IH IF
Talin-1 is a high molecular weight cytoskeletal protein, linking vinculin to the integrins, thereby linking the cytoskeleton to the extracellular matrix. It is specifically found in regions of cell-substratum contact and in lymphocytes at cell-cell contact points. Talin-1 plays a role in the assembly of actin filaments and in the migration of cells such as osteoclasts and fibroblasts.
Catalog #T0750-02A
ApplicationsSuitable for use in Immunohistochemistry, Immunoprecipitation, Immunofluorescence and Western Blot. Other applications have not been tested.
Recommended Dilutions
Immunohistochemistry (paraffin): 1:125-1:200 Requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.
Immunofluorescence: Requires fixation and permeabilisation using methanol.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
Clone No97H6
FormSupplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenHuman Talin-1
SpecificityRecognizes human Talin-1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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