This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is mainly expressed in the cortical distal tubules and collecting ducts of the kidney. The protein is highly sensitive to external pH and this, in combination with its expression pattern, suggests it may play an important role in renal potassium transport.
Applications
Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended Dilutions
Western Blot: 1:200 Rat kidney membranes Immunohistochemistry: Rat kidney sections. Optimal dilutions to be determined by the researcher.
Control Antigen
T1023-55A Preadsorption: 1ug peptide per 1ug antibody.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to aa483-499, (C)YEQL MNEYN KANSP KGT, of human TASK-2. |Epitope location: Intracellular, C-terminus. |Species sequence homology: mouse (14/17)
Form
Supplied as a liquid in PBS, pH 7.4, 1% BSA, 5% sucrose, 0.025% sodium azide.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes rat TASK2. The epitope is specific for TASK-2 and is not present in any other known proteins.
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