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You are here:Home » Antibodies » Antibodies-Microtubule-associated Proteins » Anti -Tau (Tau Protein, Microtubule-associated Protein, MAP)

Anti -Tau (Tau Protein, Microtubule-associated Protein, MAP)


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Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH
Tau protein is named for its ability to serve as a bridge for microtubule formation and stabilization. Tau in PNS neurons is 758aa in length and 110kD in size. It migrates anomalously in SDS-page. Its N-terminus binds plasma membrane components while its C-terminus binds microtubules. The microtubule-binding region contains four consecutive Tau/MAP repeats between aa561-685. Each repeat is 30aa long, Ser/Thr rich, and shows a PGGG motif. Multiple isoforms exist, ranging from 316 to 776aa in length. Various deletions occur within the first 500aa, with some isoforms also showing an absence of the second Tau repeat (aa 592-622). Between aa624-756, human Tau protein shows absolute identity to mouse and dog Tau.
Catalog #T1030-04A
ApplicationsSuitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
Clone No9L672
ConcentrationNot determined
FormSupplied as a liquid in PBS. No preservative added.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa sequence 404-441 of human Tau.
SpecificityRecognizes aa sequence 404-441 of human Tau.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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