Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Microtubule-associated Proteins » Anti -Tau, (Tau Protein, Microtubule-associated Protein, MAP)

Anti -Tau, (Tau Protein, Microtubule-associated Protein, MAP)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites E IH
Tau is a heterogeneous group of proteins that range in molecular weight from 50-67kD. They are instumental in the assembly of microtubules and have been associated with some disease states. In normal brain, tau is localized in the axons of the neurons but in some neuropathological lesions, it accumulates within the body of the neuron. Tau protein is a microtubule-associated protein predominantly localized to neuronal axons. Tau promotes tubulin polymerization and the stabilization of microtubules. Hyperphosphorylated forms of Tau are the major components of paired helical filaments (PHF) found in the neurofibrillary tangles which characterize Alzheimer’s disease. Alternate splicing of tau mRNA, glycosylation, and differential phosphorylation contribute to the heterogeneity of tau.
Catalog #T1030-30
ApplicationsSuitable for use in ELISA, Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (tissue).
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20°C or colder. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No2Q124
HostMouse
SourceBovine
ConcentrationNot determined
FormAscites fluid
PurityAscites fluid
ImmunogenBovine Tau
SpecificityTau from bovine, feline and abnormal human tau in Alzheimer’s disease tissues.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links