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You are here:Home » Antibodies » Abs to Enzymes, Deacetylase » Anti -TBL1 (TBL1X, EBI, TBL1, transducin (beta)-like 1X-linked, transducin (beta)-like 1, transducin (beta)-like 1 X-linked, TBL1XR1, transducin (beta)-like 1X-linked receptor 1, C21, DC42, FLJ12894, IRA1, TBLR1, TBL1-related protein 1, nuclear receptor co-rep

Anti -TBL1 (TBL1X, EBI, TBL1, transducin (beta)-like 1X-linked, transducin (beta)-like 1,
transducin (beta)-like 1 X-linked, TBL1XR1, transducin (beta)-like 1X-linked receptor 1,
C21, DC42, FLJ12894, IRA1, TBLR1, TBL1-related protein 1, nuclear receptor co-rep

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Transducin beta-like protein 1 (TBL1) is part of an SMRT-containing complex. Mutation of the TBL1 gene is linked with human sensorineural deafness. TBL1 displays structural and functional similarities to Tup1 and Groucho corepressors, sharing their ability to interact with histone H3.
Catalog #T1510-01
Alternate Name TBL1X, EBI, TBL1, transducin (beta)-like 1X-linked, transducin (beta)-like 1, transducin (beta)-like 1 X-linked, TBL1XR1, transducin (beta)-like 1X-linked receptor 1, C21, DC42, FLJ12894, IRA1, TBLR1, TBL1-related protein 1, nuclear receptor co-repressor/HDAC3 complex subunit
Domain Information FOG: WD40 repeat [General function prediction only]; Lissencephaly type-1-like homology motif
Gene Ontology Terms hearing; vision; signal transduction
Application(s) Suitable for use in ELISA, Western Blot. Other applications not tested.
Western blot: Approx 65-70kD band seen in Human Brain lysate. Recommended for use at 3-5ug/ml.
Staining (4ug/ml) of Human Brain lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Peptide BlockingCorresponding peptide is available for Peptide Blocking studies. See T1510-01-P. Antibody is typically 0.5mg/ml and peptide is supplied as a 100ul pellet. When peptide is reconstituted in 200ul water, the concentration would also be 0.5mg/ml. To start, the best ratio would be 1:1 (molar excess of peptide relative to antibody when identical volumes are mixed). Mix equal volumes of peptide and antibody at the required dilution and leave at ambient temperature. It is best is to have two identical blots to be incubated with equal amount of antibody, but one with the antibody pre-adsorbed to the peptide for 20min. Then incubate and develop the two blots in parallel.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, pH 7.2, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSASDGSVCVLDLRK, C Terminus
SpecificityThis antibody is also expected to recognize the human protein TBLR1 (NP_078941), which is very similar. Species Crossreactivity: human, mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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