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You are here:Home » Antibodies » Abs to Cancer Markers » Anti -TPT1 (TCTP, Translationally-controlled tumor protein, p23, Histamine-releasing Factor, HRF, Fortilin)

Anti -TPT1 (TCTP, Translationally-controlled tumor protein, p23, Histamine-releasing
Factor, HRF, Fortilin)


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Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IP IH IC FC
TCTP (translationally-controlled tumor protein) has a potent anti-apoptotic function. Calcium up-regulates TCTP transcription, suggesting a role for TCTP in intracellular calcium homeostasis (1). It is apparently a histamine-releasing factor identified from a protein-inducing secretion of histamine from basophiles, with an extensive homology to TPT1 (2). TCTP is also a tubulin-binding protein that associates with microtubules in a cell-cycle dependent fashion (3). Furthermore, it is suggested to regulate cellular pluripotency (4).
Catalog #T2040-39B
ApplicationsSuitable for use in Western Blot, Immunocytochemistry, Immunoprecipitation, Flow cytometry and Immunohistochemistry. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:10,000-1:50,000
Immunohistochemistry: 1:250-1:500
Immunocytochemistry: 1:250-1:500
Immunoprecipitation: 1:10-1:100
Flow cytometry: 1:10-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
Clone NoEPR5540
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.2, 0.05% BSA, 0.01% sodium azide, 50% glycerol.
ImmunogenSynthetic peptide corresponding to residues in human TPT1.
SpecificityRecognizes human TPT1. Species crossreactivity: Mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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