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Abs to Telomere/Telomerase
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Anti -Telomerase, Human (EST2, hEST2, TCS1, Telomerase Catalytic Subunit, Telomerase-associated protein 2, Telomere Reverse Transcriptase, TERT, TP2, TRT)
Anti -Telomerase, Human (EST2, hEST2, TCS1, Telomerase Catalytic Subunit,
Telomerase-associated protein 2, Telomere Reverse Transcriptase, TERT, TP2, TRT)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Ascites |
B IH FC IF |
|
| Telomeres are nucleoprotein structures at the ends of eukaryotic chromosomes. They regulate several crucial cellular functions and participate in the control of complex phenotypes, such as aging and cancer. Cell immortalization is strongly associated with the stabilization of telomere length. Therefore, it is suggested that cancer cells achieve immortalization in part through illegitimate activation of telomerase expression. hTERT is the rate-limiting catalytic subunit of telomerase. | | | Catalog # | T2399-14 | | Applications | Suitable for use in Flow Cytometry/FACS analysis, Immunofluorescence, Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry: Paraffin | | Optimal dilutions to be determined by the researcher. | | Recomme | nded Secondary Antibodies: | | I1905-18D IgM (X-Adsorbed) (FITC) Pab GtxMo | | I1905-04A IgM (X-Adsorbed) (PE) Pab GtxMo | | I1905-28A IgM (X-Adsorbed) (HRP) Pab GtxMo | | I1905-15U IgM (AP) Pab GtxMo | | Positive Controls | 293T whole cell lysates, HeLa whole cell lysates | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgM | | Clone No | 4i236 | | Host | Mouse | | Source | Human | | Concentration | Not Determined | | Form | Supplied as liquid, 0.05% sodium azide. | | Purity | Ascites | | Immunogen | Full-length recombinant human TERT from insect cells. Cellular Localization: Nuclear | | Specificity | Recognizes human Telomerase at ~127kD. May see an additional background band at ~110kD. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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