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You are here:Home » Antibodies » Abs to THAP Domain-containing Proteins » Anti -THAP11 (THAP Domain Containing 11, Ronin, CTG-B43a, CTG-B45d, HRIHFB2206)

Anti -THAP11 (THAP Domain Containing 11, Ronin, CTG-B43a, CTG-B45d, HRIHFB2206)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IC
The protein encoded by this gene contains a THAP domain, which is a conserved DNA-binding domain that has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases. THAP11, also known as Ronin, is a 3644kD member of the Thanatos-associated protein family. It is ubiquitously expressed and through its repression of cMyc transcription, blocks cell proliferation. Human THAP11 is 314aa in length. It contains a DNA binding THAP zinc-finger domain (aa5-81), an NLS (aa98-104 a polyGln region (aa104-146 an Ala-rich segment (aa 197-221 and a C-terminal coiled coil region (aa255-305 THAP11 is phosphorylated on Thr25. Over aa226-314 human and mouse THAP11 are 100% identical in aa sequence.
Catalog #T3700-02
ApplicationsSuitable for use in Western Blot and Immunocytochemistry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No11D112
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a lyophilized powder in PBS with Trehalose Reconstitute with sterile PBS.
PurityPurified by Protein A/G affinity chromatography.
ImmunogenRecombinant corresponding to Gly226Met314 in THAP11 expressed in E. coli (Q96EK4).
SpecificityRecognizes human THAP11.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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