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You are here:Home » Biochemicals » Biochem-Antibiotics » Thiolutin (N-acetylpyrrothine, Farcinicine, Acetopyrrothine)

Thiolutin (N-acetylpyrrothine, Farcinicine, Acetopyrrothine)


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Thiolutin is an antibiotic first described by Tanner and co-workers in 1950. Resurgent interest in this class of microbial metabolite was stimulated by the discovery of their selective antitumor activity. Thiolutin has been shown to be a potent inhibitor of bacterial and yeast RNA polymerases and inhibitor of mannan and glucan formation in fungi. Studies have shown that thiolutin suppresses tumor cell-induced angiogenesis in vivo.
Catalog #T3786-15
DMSO and DMF, partially soluble in methanol and ethanol while poorly soluble in water
CAS Number87-11-6
Molecular FormulaC8H8N2O2S2
Molecular Weight228.295
SourceStreptomyces sp.
Purity> 98% by HPLC
FormYellow orange solid
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesN-acetylpyrrothine, Farcinicine, Acetopyrrothine

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