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Abs to Thioredoxin
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Anti -TXNDC4 (Endoplasmic Reticulum Resident Protein 44, ER Protein 44, ERp44, Thioredoxin Domain-containing Protein 4, KIAA0573, ERP44, UNQ532/PRO1075)
Anti -TXNDC4 (Endoplasmic Reticulum Resident Protein 44, ER Protein 44, ERp44, Thioredoxin
Domain-containing Protein 4, KIAA0573, ERP44, UNQ532/PRO1075)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B |
|
| Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum. | | | Catalog # | T5010-11J1 | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 1:32,000 | | Western Blot: 0.2-0.6ug/ml, observed in lysates of cell line K562 on ~47kD bands | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to C-EQKDSDNYRVFER, from human TXNDC4, at the internal region of the protein (NP_055866.1). | | Specificity | Recognizes human TXNDC4. Species sequence homology: Bovine, mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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