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You are here:Home » Antibodies » Abs to Thioredoxin » Anti -TXNDC4 (Endoplasmic Reticulum Resident Protein 44, ER Protein 44, ERp44, Thioredoxin Domain-containing Protein 4, KIAA0573, ERP44, UNQ532/PRO1075)

Anti -TXNDC4 (Endoplasmic Reticulum Resident Protein 44, ER Protein 44, ERp44, Thioredoxin
Domain-containing Protein 4, KIAA0573, ERP44, UNQ532/PRO1075)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
Catalog #T5010-11J1
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Western Blot: 0.2-0.6ug/ml, observed in lysates of cell line K562 on ~47kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-EQKDSDNYRVFER, from human TXNDC4, at the internal region of the protein (NP_055866.1).
SpecificityRecognizes human TXNDC4. Species sequence homology: Bovine, mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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