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You are here:Home » Antibodies » Abs to Thioredoxin » Anti -Thioredoxin Reductase 1 (Thioredoxin Reductase 1 Cytoplasmic, Thioredoxin Reductase TR1, TR1, TR 1, TR, TRXR 1, TRXR1, TRXR-1, TXNR, TXNRD1, Gene-associated with Retinoid IFN-induced Mortality 12 Protein, GRIM 12, GRIM-12, KM-102-derived Reductase-like Fa

Anti -Thioredoxin Reductase 1 (Thioredoxin Reductase 1 Cytoplasmic, Thioredoxin Reductase
TR1, TR1, TR 1, TR, TRXR 1, TRXR1, TRXR-1, TXNR, TXNRD1, Gene-associated with Retinoid
IFN-induced Mortality 12 Protein, GRIM 12, GRIM-12, KM-102-derived Reductase-like Fa

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
This protein is a pyridine nucleotide oxidoreductase which reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. It is thought to function as a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine residue which is required for the catalytic activity. Alternative splicing results in several transcript variants encoding the same protein. Additional transcript variants have been described but their biological validity has not been determined.
Catalog #T5010-14B
ApplicationsSuitable for use in Peptide ELISA and Western Blot. Other applications not tested.
Recommended DilutionPeptide ELISA: 1:32,000
Western Blot: 0.1-1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris-saline, pH 7.3 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa485-497, TKRSGASILQAGC, representing the C-Terminus of the human protein, according to NP_003321.
SpecificityRecognizes human Thioredoxin Reductase 1. Species crossreactivity: porcine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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