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You are here:Home » Antibodies » Abs to Thrombopoietin » Anti -Thrombopoietin Receptor (TPO-R, Myeloproliferative Leukemia Protein, Proto-oncogene c-Mpl, CD110, TPOR) (PE)

Anti -Thrombopoietin Receptor (TPO-R, Myeloproliferative Leukemia Protein, Proto-oncogene
c-Mpl, CD110, TPOR) (PE)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
Thrombopoietin receptor (Tpo R), also known as myeloproliferative leukemia protein (c-mpl), is a 95kD type I transmembrane protein that is a member of the type I cytokine receptor family within the hematopoietin/cytokine receptor superfamily.1-4 The 635aa full-length human Tpo R contains a 25aa signal sequence, a 466aa extracellular domain with a ligand binding domain and two fibronectin type III domains, a transmembrane (TM) domain and a cytoplasmic domain. The extracellular domain of human Tpo R shares 78%, 76%, 81%, 82% and 80% aa identity with mouse, rat, cow, dog, and horse, respectively.
Catalog #T5050-50B
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionFlow Cytometry: 10ul labels 10e6 cells
Optimal dilutions to be determined by the researcher.
HybridomaMyeloma cells with B cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C. Stable for 12 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. (PE) conjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No11D72
HostMouse
SourceHuman
Concentration~0.0.08mg/ml
FormSupplied as a liquid in saline, 5% BSA, 0.1% sodium azide. Labeled with R-Phycoerythrin (PE).
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant protein corresponding to human Thrombopoetin receptor expressed in NSO cells (P40238).
SpecificityRecognizes human Thrombopoietin R.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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