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Anti -Thrombospondin Type-1 Domain-containing Protein 1 (THSD1, Transmembrane Molecule with Thrombospondin Module, Tmtsp)
Anti -Thrombospondin Type-1 Domain-containing Protein 1 (THSD1, Transmembrane Molecule
with Thrombospondin Module, Tmtsp)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
FC |
|
| THSD1 (thrombospondin type 1 domain-containing protein 1; also TMTSP) is a 90-100kD type I transmembrane protein that is reminiscent of Unc5h proteins. It is expressed on embryonic endothelial and hematopoietic stem cells, and may be involved in cell-cell interactions. Mature human THSD1 contains a 388aa extracellular domain (ECD) (aa25-412) and a 418aa cytoplasmic region (aa434-851). The ECD possesses three Ig-like domains (aa156-316) and one TSP type-1 domain (aa340-393). There is one potential alternate start site at Met380, and two splice variants, one of which shows a deletion of aa341-393, and a second that shows a 36aa substitution for aa394-851, generating a soluble form. Over aa25-361, human THSD1 is 76% aa identical to mouse THSD1. | | | Catalog # | T5101-09 | | Applications | Suitable for use in Flow Cytometry. Other applications not tested. | | Recommended Dilution | Flow Cytometry: 25ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS, sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 9j10 | | Host | Mouse | | Source | Human | | Concentration | As reported | | Form | Supplied as a lyophilized powder from 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with sterile PBS, sterile 40-50% glycerol. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | NS0-derived, recombinant human THSD1 (aa25-361). | | Specificity | Recognizes human THSD1. Species sequence homology: mouse (76%). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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