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You are here:Home » Antibodies » Abs to Thrombospondin » Anti -Thrombospondin Type-1 Domain-containing Protein 1 (THSD1, Transmembrane Molecule with Thrombospondin Module, Tmtsp)

Anti -Thrombospondin Type-1 Domain-containing Protein 1 (THSD1, Transmembrane Molecule
with Thrombospondin Module, Tmtsp)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
THSD1 (thrombospondin type 1 domain-containing protein 1; also TMTSP) is a 90-100kD type I transmembrane protein that is reminiscent of Unc5h proteins. It is expressed on embryonic endothelial and hematopoietic stem cells, and may be involved in cell-cell interactions. Mature human THSD1 contains a 388aa extracellular domain (ECD) (aa25-412) and a 418aa cytoplasmic region (aa434-851). The ECD possesses three Ig-like domains (aa156-316) and one TSP type-1 domain (aa340-393). There is one potential alternate start site at Met380, and two splice variants, one of which shows a deletion of aa341-393, and a second that shows a 36aa substitution for aa394-851, generating a soluble form. Over aa25-361, human THSD1 is 76% aa identical to mouse THSD1.
Catalog #T5101-09
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionFlow Cytometry: 25ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS, sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No9j10
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a lyophilized powder from 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with sterile PBS, sterile 40-50% glycerol.
PurityPurified by Protein G affinity chromatography.
ImmunogenNS0-derived, recombinant human THSD1 (aa25-361).
SpecificityRecognizes human THSD1. Species sequence homology: mouse (76%).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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