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Anti -Thymine Dimer (Cyclobutane Pyrimidine Dimer, CPD)
Anti -Thymine Dimer (Cyclobutane Pyrimidine Dimer, CPD)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
IH IC Gel |
|
| This antioody is intended for the detection of DNA damage as a result of UV irradiation. | | | Catalog # | T5151-09 | | Hybridoma | Mouse myeloma (P3/X63-Ag8) x immunized mouse (Balb/c) spleen cells | | Applications | Suitable for use in Immunohistochemistry, Immunocytochemistry, Southern Blot, Northern Blot, and Dot Blot. Other applications have not been tested. | | Recommended Dilution | In situ Hybridization: 1:40-1:80. Frozen sections of fixed tissue or formalin-fixed, paraffin-embedded sections are recommended. | | Southern, Northern and Dot Blot: For the detection of thymine dimers in UV-damaged DNA and thymine-dimerized DNA probes used for in situ. (reported to work, but no data is available) | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | KTM53 | | Host | Mouse | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS containing 0.1% sodium azide and protein stabilizer | | Purity | Purified by Protein A affinity chromatography | | Immunogen | UV-irradiated salmon sperm DNA | | Specificity | Recognizes thymine dimers produced by UV irradiation in double- or single- stranded DNA. Does not react with (6-4) photo products. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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