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You are here:Home » Antibodies » Abs to RNA Processing » Anti -TIA1 (Nucleolysin TIA-1 Isoform p40, RNA-binding Protein TIA-1, T-cell-restricted Intracellular Antigen-1, TIA-1, p40-TIA-1)

Anti -TIA1 (Nucleolysin TIA-1 Isoform p40, RNA-binding Protein TIA-1, T-cell-restricted
Intracellular Antigen-1, TIA-1, p40-TIA-1)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15kD protein that is thought to be derived from the carboxyl terminus of the 40kD product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.
Catalog #T5461-95B
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:128,000
Western Blot: 0.1-0.3ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 3.75ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-PKSTYESNTKQ from an internal region of human TIA1.
SpecificityRecognizes human TIA1. Species sequence homology: Canine, mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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