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You are here:Home » Antibodies » Abs to T Cells » Anti -Tim3 (T Cell Immunoglobulin and Mucin Domain Containing Protein 3) (PE)

Anti -Tim3 (T Cell Immunoglobulin and Mucin Domain Containing Protein 3) (PE)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified FC
Tim-3 is expressed on differentiated Th1 cells, but not on Th2 cells. It enhances macrophage activation, inhibits Th1-mediated auto- and alloimmune responses and promotes immunological tolerance. Galectin-9 is a ligand for Tim-3 and induces Th1 cell death. Signalling through the Tim-3 pathway may therefore negatively regulate Th1 responses.
Catalog #T5469-92E
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionFlow Cytometry: 1:5-1:10 10ul labels 1x10e6 cells in 100ul.
Optimal dilutions to be determined by the researcher.
Recommended Negative ControlsRat IgG2a NEGATIVE CONTROL (PE)
Rat IgG2a NEGATIVE CONTROL (PE)
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid for 6 months. Dilute only prior to immediate use. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity.
CAS Numbern/a
Clone TypeMonoclonal
IsotypeIgG2a
Clone No9F95
HostRat
SourceMouse
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
SpecificityRecognizes mouse T-cell immunoglobulin and mucin domain-containing protein 3 (Tim-3), a member of the Tim family type I membrane proteins.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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