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You are here:Home » Antibodies » Abs to T Cells, Lymphocytes » Anti -TIM3 (Hepatitis A Virus Cellular Receptor 2, HAVcr-2, T-cell Immunoglobulin and Mucin Domain-containing Protein 3, TIMD-3, T-cell Membrane Protein 3, TIM-3, HAVCR2, TIMD3) (PerCP)

Anti -TIM3 (Hepatitis A Virus Cellular Receptor 2, HAVcr-2, T-cell Immunoglobulin and
Mucin Domain-containing Protein 3, TIMD-3, T-cell Membrane Protein 3, TIM-3, HAVCR2,
TIMD3) (PerCP)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified FC
Mouse Tim-3 (T-cell Immunoglobulin- and Mucin -domain- containing molecule -3) is a type I transmembrane protein that contains an immunoglobulin V-type domain followed by a mucin-like domain in its extracellular region.1 Tim-3 is expressed on Th1 and Tc1 cells and is hypothesized to regulate macrophage activation.1 Binding of Tim-3 to Tim-3 Ligand on CD4+ T cells suggests that these proteins function in regulating Th1 cell expansion and/or activation,2 and suggests a role for Tim-3 in inducing tolerance.3 Mouse models utilizing antibodies to Tim-3 reveal a role for Tim-3 in immune-mediated diseases such as asthma and multiple sclerosis.2, 4
Catalog #T5469-92R
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
HybridomaMyeloma cells with B cells from Balb/c mice.
Absorption 482-564nm
Emission 675nm
Storage and StabilityMay be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. PerCP conjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG2A
Clone No11n191
HostRat
SourceMouse
ConcentrationAs reported
FormSupplied as a liquid in 1ml saline, 0.5% BSA, 0.1% sodium azide. Labeled with PerCP.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant corresponding to aa20-193 from mouse TIM-3 expressed in NSO cells (Q8VIM0).
SpecificityRecognizes mouse TIM-3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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