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You are here:Home » Antibodies » Antibodies-Protease Inhibitors » Anti -Tissue Factor Pathway Inhibitor 2 (TFPI2, TFPI-2, Placental Protein 5, PP5)

Anti -Tissue Factor Pathway Inhibitor 2 (TFPI2, TFPI-2, Placental Protein 5, PP5)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Tissue factor pathway inhibitor 2, also known as TFPI2, is a human gene which is located at 7q22. It is an important regulator of the extrinsic pathway of blood coagulation through its ability to inhibit factor Xa and factor VIIa-tissue factor activity. After a 22-residue signal peptide, the mature TFPI2 protein contains 213aa with 18 cysteines and 2 canonical N-linked glycosylation sites. The purified recombinant TFPI2 strongly inhibited the amidolytic activities of trypsin and the factor VIIa-tissue factor complex.1 The latter inhibition was markedly enhanced in the presence of heparin. Mouse TFPI2 mRNA is highly expressed in developing mouse placenta, as in human. And there are also high transcript levels in adult mouse liver and kidney.
Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Catalog #T5576-22
Recommended DilutionWestern Blot:1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile dH20. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
ConcentrationAs reported
FormSupplied as a lyophilized powder from PBS, pH 7.4, 5% BSA, 0.05% thimerosal, 0.05% sodium azide. Reconstitute with sterile dH2O.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to a sequence at the middle region of human TFPI2, identical to the related rat and mouse sequence.
SpecificityRecognizes human TFPI2. Species Sequence Homology: mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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