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You are here:Home » Biochemicals » Biochem-Antibiotics » Clavulanate Potassium

Clavulanate Potassium


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Clavulanic acid is a beta-lactam antibiotic produced by several species of the genus Streptomyces. The free acid degrades and is isolated and maintained as either the sodium or potassium salt. Clavulanate is a weak antibiotic but is a potent inhibitor of beta- lactamases. In combination with penicillin and cephalosporins it shows potent synergistic activity. Clavulanic acid is a suicide inhibitor, covalently binding to a serine residue in the active site of the beta-lactamase.
Catalog #T5579-01
SourceStreptomyces sp.
SolubilitySoluble in water, DMSO, Methanol, Ethanol and DMF.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number61177-45-5
Molecular FormulaC8H8NO5K
Molecular Weight~237.25
Purity~98% (HPLC)
FormSupplied as a white to off-white powder
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
Alternate namesPotassium [2R-(2 ,3Z,5 )]-3-(2-hydroxyethylidene)-7-oxo-4-oxa- 1-azabicyclo[3.2.0]heptane-2-carboxylate

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