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You are here:Home » Antibodies » Abs to Toll Like Receptors (TLR) » Anti -TLR1 (Toll Like Receptor 1, Toll-like Receptor 1 Precursor, CD281, CD281 Antigen, DKFZp547I0610, DKFZp564I0682, KIAA0012, MGC104956, MGC126311, MGC126312, rsc786, Similar to Drosophila Toll Protein, TIL, Toll (Drosophila) Homolog, Toll/Interleukin 1 Recep

Anti -TLR1 (Toll Like Receptor 1, Toll-like Receptor 1 Precursor, CD281, CD281 Antigen,
DKFZp547I0610, DKFZp564I0682, KIAA0012, MGC104956, MGC126311, MGC126312, rsc786, Similar
to Drosophila Toll Protein, TIL, Toll (Drosophila) Homolog, Toll/Interleukin 1 Recep

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B FC
The Toll-like receptor (TLR) family in mammals are comprised of a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and an IL-1 receptor motif in the cytoplasmic domain. The TLRs could constitute an important and unrecognized component of innate immunity in humans. In mice, TLR1 interacts with TLR2 and coexpression of TLR1 and TLR2 enhance the NF-kappaB activation in response to a synthetic lipopeptide. They recognize the lipid configuration of the native mycobacterial lipoprotein as well as several triacylated lipopeptides.
Catalog #T8050-01F
ApplicationsSuitable for use in Flow Cytometry and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Positive Control Ramos
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenThis antibody was developed against a KLH-conjugated synthetic peptide corresponding to a sequence within amino acids 400-450 of human TLR1. It will not cross-react with mouse TLR1.
SpecificityIn Ramos, an 87kD band is observed. Species Crossreactivity: Human, Rat
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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