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You are here:Home » Antibodies » Abs to Toll Like Receptors (TLR) » Anti -TLR1 (CT) (Toll-like Receptor 1, CD281, DKFZp547I0610, DKFZp564I0682, KIAA0012, MGC104956, MGC126311, MGC126312, rsc786, TIL, Toll/interleukin-1 receptor-like protein, Toll-like receptor 1)

Anti -TLR1 (CT) (Toll-like Receptor 1, CD281, DKFZp547I0610, DKFZp564I0682, KIAA0012,
MGC104956, MGC126311, MGC126312, rsc786, TIL, Toll/interleukin-1 receptor-like protein,
Toll-like receptor 1)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR1 recognizes peptidoglycan and (triacyl) lipoproteins on pathogens, especially gram-positive bacteria. TLR1 is found on the surface of macrophages and neutrophils.
Catalog #T8050-01H
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlRaji cell lysate.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.25mg/ml
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to humanTLR1.
SpecificityRecognizes the C-terminal domain of human TLR1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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